2021
[38] Ricardo G. Teixeira, Dimas C. Belisario, Xavier Fontrodona, Isabel Romero, Ana Isabel Tomaz, M. Helena Garcia, Chiara Riganti, Andreia Valente*, “Unprecedented collateral sensitivity for cisplatin-resistant lung cancer cells presented by new ruthenium organometallic compounds”, Inorganic Chemistry Frontiers, 2021. DOI: 10.1039/d0qi01344g
[37] Diogo Sequeira, Pedro V. Baptista, Ruben Valente, M. Fátima M. Piedade, M. Helena Garcia, Tânia S. Morais* and Alexandra R. Fernandes*, "Cu(i) complexes as new antiproliferative agents against sensitive and doxorubicin resistant colorectal cancer cells: synthesis, characterization, and mechanisms of action", Dalton Trans., 2021, 50, 1845-1865
2020
[36] Ricardo G. Teixeira, Fernanda Marques, M. Paula Robalo, Xavier Fontrodona, M. Helena Garcia, Simonetta Geninatti Crich, Clara Viñas*, Andreia Valente*, “Ruthenium carboranyl complexes with 2,2’-bipyridine derivatives for potential bimodal therapy application”, Accepted at RSC Advances, 2020.
[35] João Franco Machado, Diogo Sequeira, Fernanda Marques, M. Fátima M. Piedade, Maria J. Villa de Brito, M. Helena Garcia, Alexandra R. Fernandes* and Tânia S. Morais*, “New copper(i) complexes selective for prostate cancer cells”, Dalton Trans., 2020, 49, 12273-12286
[34] Pilon A, Brás AR, Côrte-Real L, Avecilla F, Costa PJ, Preto A, Garcia MH, Valente A*, “A new family of iron(II)-cyclopentadienyl compounds shows strong activity against colorectal and triple negative breast cancer cells”. Molecules. 2020 Mar 30;25(7). pii: E1592.
[33] João Franco Machado, Miguel Machuqueiro, Fernanda Marques, M. Paula Robalo, M. Fátima M. Piedade, M. Helena Garcia, João D. G. Correia*, Tânia S. Morais*, “Novel “ruthenium cyclopentadienyl”–peptide conjugate complexes against human FGFR(+) breast cancer”. Dalton Trans., 2020, 49, 5974-5987
2019
[32] Catarina Bravo, M. Paula Robalo, Fernanda Marques, Alexandra R. Fernandes, Diogo A. Sequeira, M. Fátima M. Piedade, M. Helena Garcia, Maria J. Villa de Brito*, Tânia S. Morais*, "First heterobimetallic Cu(i)–dppf complexes designed for anticancer applications: synthesis, structural characterization and cytotoxicity". New J. Chem., 2019, 43, 12308-12317
[31] L. Côrte-Real, B. Karas, A. R. Brás, A. Pilon, F. Avecilla, F. Marques, A. Preto, B. T. Buckley, K. R. Cooper, C. Doherty, M. H. Garcia*, A. Valente*, “Ruthenium-Cyclopentadienyl Bipyridine-Biotin Based Compounds: Synthesis and Biological Effect”. Inorganic Chemistry 2019, 58, 9135−9149.
[30] Lurdes Gano, Teresa Pinheiro, António P. Matos, Francisco Tortosa, Tiago F. Jorge, M. S. Gonçalves, M. Martins, Tânia S. Morais, Ana Isabel Tomaz, Andreia Valente, M. Helena Garcia, Fernanda Marques, “Antitumour and Toxicity Evaluation of a Ru(II)-Cyclopentadienyl Complex in a Prostate Cancer Model by Imaging Tools”. Anticancer Agents Med Chem. 2019 Mar 18.
[29] Brittany Karas, Leonor Côrte-Real, Andreia Valente, Keith R. Cooper, Brian T. Buckley, “Novel screening of transition metal-based anticancer compounds using zebrafish embryo larval assay and ICPMS analysis”. J. Appl. Toxicology 2019, 1-8.
[28] T. Moreira, R. Francisco, E. Comsa, S. Duban-Deweer, V. Labas, A.-P. Teixeira-Gomes, L. Combes-Soia, F. Marques, A. Matos, A. Favrelle, C. Rousseau, P. Zinck, P. Falson, M. H. Garcia, A. Preto, A. Valente*, “Polymer “ruthenium-cyclopentadienyl” conjugates - new emerging anti-cancer drugs”. European Journal of Medicinal Chemistry 2019, 168, 373-384.
[27] L. Côrte-Real, B. Karas, P. Gírio, A. Moreno, F. Avecilla, F. Marques, B. T. Buckley, K. R. Cooper, C. Doherty, P. Falson, M. H. Garcia*, A. Valente*, “Unprecedented inhibition of P-gp activity by a novel ruthenium-cyclopentadienyl compound bearing a bipyridine-biotin ligand”, European Journal of Medicinal Chemistry, 2019, 163, 853-863.
2018
[26] L. Côrte-Real, R. G. Teixeira, P. Gírio, E. Comsa, A. Moreno, R. Nasr, H. Baubichon-Cortay, F. Avecilla, F. Marques, M. P. Robalo, P. Mendes, J. P. P. Ramalho, M. H. Garcia, P. Falson*, A. Valente*, “Methyl-cyclopentadienyl Ruthenium Compounds with 2,2′-Bipyridine Derivatives Display Strong Anticancer Activity and Multidrug Resistance Potential”. Inorganic Chemistry, 2018, 57, 4629−4639.
[25] R. G. Teixeira, A. Sanches, L. Côrte-Real, R. Tatikonda, A. R. Brás, M. P. Robalo, F. Avecilla, M. H. Garcia, A. Preto, M. Haukka, A. Valente*, “Novel ruthenium methylcyclopentadienyl complex bearing a bipyridine perfluorinated ligand shows strong activity towards colorectal cancer cells”. European Journal of Medicinal Chemistry, 143, 2018, 503-514.
[24] Tânia S. Morais,* Yann Jousseaume, M. Fátima M. Piedade, Catarina Roma-Rodrigues, Alexandra R. Fernandes, Fernanda Marques, Maria J. Villa de Brito*, M. Helena Garcia, “Important cytotoxic and cytostatic effects of new copper(i)–phosphane compounds with N,N, N,O and N,S bidentate ligands”. Dalton Trans., 2018, 47, 7819-7829
2017
[23] A. Pilon, P. Gírio, G. Nogueira, F. Avecilla, H. Adams, J. Lorenzo, M. H. Garcia*, A. Valente*, “New iron cyclopentadienyl complexes bearing different phosphane co-ligands: structural factors vs. cytotoxicity”, Journal of Organometallic Chemistry, 852, 2017, 34-42.
[22] N. Mendes, F. Tortosa, A. Valente, F. Marques, A. Matos, T. S. Morais, A. I. Tomaz, F. Gärtner, M. H. Garcia, “In vivo Performance of a Ruthenium-cyclopentadienyl Compound in an Orthotopic Triple Negative Breast Cancer Model”, Anti-cancer Agents in Medicinal Chemistry Vol. 17, No. 1, 126-136, 2017.
[21] João Lopes, David Alves, Tânia S.Morais, Paulo J. Costa, M. Fátima M. Piedade, Fernanda Marques, Maria J. Villa de Brito, M. Helena Garcia, “New copper(I) and heteronuclear copper(I)–ruthenium(II) complexes: Synthesis, structural characterization and cytotoxicity”. Journal of Inorganic Biochemistry, 169, 2017, Pages 68-78.
2016
[20] G. Nogueira, O. Dömötör, A. Pilon, M. P. Robalo, F. Avecilla, M. H. Garcia, É. A. Enyedy*, A. Valente*, “η6-(2-Phenoxyethanol) ruthenium(II)-complexes of 2,2’-bipyridine and its derivatives: solution speciation and kinetic behaviour”, J. Organomet. Chem. 2016, 820, 20-29.
[19] T. S. Morais, A. Valente, A. Is. Tomaz, F. Marques, M. H. Garcia, “Tracking anti-tumor metallodrugs: promising agents with the Ru(II)- and Fe(II)-cyclopentadienyl scaffolds”, Future Medicinal Chemistry 2016, 8, 527-544. – selected as special report for the April issue
2015
[18] L. Côrte-Real, F. Marques, M. P. Robalo, G. Nogueira, F. Avecilla, F. C. Santos, A. I. Tomaz, M. H. Garcia*, A. Valente*, “The significant role of coligands in novel ruthenium(II)-cyclopentadienyl bipyridine derivatives: ranging from non-cytotoxic to highly cytotoxic compounds”, Journal of Inorganic Biochemistry 2015, 150, 148–159.
2014
[17] F. Marques, L. Côrte-Real, F. Mendes, J. Coimbra, T. Morais, A. I. Tomaz, A. Valente, M. H. Garcia, I. Santos, M. Bicho, “Anticancer Activity of Structural Related Ruthenium(II) Cyclopentadienyl complexes”, Journal of Biological Inorganic Chemistry 2014, 19(6):853-67.
[16] A. Valente,* M. H. Garcia, “Syntheses of macromolecular ruthenium compounds: a new approach to the search of anticancer drugs”, Inorganics 2014, 2, 96-114.
[15] A. Valente, A. M. Santos, L. Côrte-Real, M. P. Robalo, V. Moreno, M. Font-Bardia, T. Calvet, J. Lorenzo, M. H. Garcia, “New iron(II) cyclopentadienyl derivative complexes: synthesis and antitumor activity against human leukemia cancer cells”, Journal of Organometallic Chemistry 2014, 756, 52-60.
[14] Tânia S. Morais, Filipa C. Santos, Tiago F. Jorge, Leonor Côrte-Real, Paulo J. Amorim Madeira, Fernanda Marques, M. Paula Robalo, António Matos, Isabel Santos, M. Helena Garcia*, “New water-soluble ruthenium(II) cytotoxic complex: Biological activity and cellular distribution”. Journal of Inorganic Biochemistry, 130, 2014, Pages 1-14
2013
[13] A. Valente,* M. H. Garcia, F. Marques, Y. Miao, C. Rousseau, P. Zinck, “First polymer “ruthenium-cyclopentadienyl” complex as potential anticancer agent”, Journal of Inorganic Biochemistry 2013, 127, 79-81.
[12] C.P. Matos, A. Valente, F. Marques, M.P. Robalo, P. Adão, J.C. Pessoa, I. Santos, M.H. Garcia, A. I. Tomaz, “New polydentate Ru(III)-Salan complexes: Synthesis, characterization, anti-tumour activity and interaction with human serum proteins”, Inorganica Chimica Acta 2013, 394, 616-626.
[11] Tânia S.Morais, Filipa Santos, Leonor Côrte-Real, Fernanda Marques, M. Paula Robalo, Paulo J. Amorim Madeira, M. Helena Garcia, “Biological activity and cellular uptake of [Ru(η5-C5H5)(PPh3)(Me2bpy)][CF3SO3] complex”. Journal of Inorganic Biochemistry, 122, 2013, Pages 8-17
[10] Leonor Côrte-Real, António P. Matos, Irina Alho, Tânia S. Morais, Ana Isabel Tomaz, Maria Helena Garcia, Isabel Santos, Manuel P. Bicho, Fernanda Marques, “Cellular Uptake Mechanisms of an Antitumor Ruthenium Compound: The Endosomal/Lysosomal System as a Target for Anticancer Metal-Based Drugs”. Microscopy and Microanalysis, 19, 2013, pp. 1122-1130
[9] Tânia S. Morais, Filipa C. Santos, Leonor Corte-Real, M. Helena Garcia*, “Exploring the effect of the ligand design on the interactions between [Ru(η5-C5H5)(PPh3)(N,O)][CF3SO3] complexes and human serum albumin”. Journal of Inorganic Biochemistry, 129, 2013, Pages 94-101
[8] Ana Cristina Gonçalves, Tânia S. Morais, M. Paula Robalo, Fernanda Marques, Fernando Avecilla, Cristina P. Matos, Isabel Santos, Ana Isabel Tomaz, M. Helena Garcia*, “Important cytotoxicity of novel iron(II) cyclopentadienyl complexes with imidazole based ligands”. Journal of Inorganic Biochemistry, 129, 2013, Pages 1-8
2012
[7] Ana Isabel Tomaz,* Tamás Jakusch, Tânia S. Morais, Fernanda Marques, Rodrigo F. M. de Almeida, Filipa Mendes, Éva A. Enyedy, Isabel Santos, João Costa Pessoa, Tamás Kiss, M. Helena Garcia, “[RuII(η5-C5H5)(bipy)(PPh3)]+, a promising large spectrum antitumor agent: Cytotoxic activity and interaction with human serum albumin”. Journal of Inorganic Biochemistry, 117, 2012, Pages 261-269
[6] Paulo J. Amorim Madeira*, Tânia S. Morais, Tiago J. L. Silva, Pedro Florindo, M. Helena Garcia, “Gas‐phase behaviour of Ru(II) cyclopentadienyl‐derived complexes with N‐coordinated ligands by electrospray ionization mass spectrometry: fragmentation pathways and energetics”. Rapid Communications in Mass Spectrometry, 26, 2012, 1675-1686.
[5] Tânia S. Morais, M. Helena Garcia*, M. Paula Robalo, M. F. M. Piedade, M. Teresa Duarte, M. José Villa de Brito, Paulo J. Amorim Madeira, “Synthesis and structural characterization of new piano-stool ruthenium(II) complexes bearing 1-butylimidazole heteroaromatic ligand”. Journal of Organometallic Chemistry, 713, 2012, Pages 112-122
[4] Tânia S. Morais, Tiago J. L. Silva, Fernanda Marques, M. Paula Robalo, Fernando Avecilla, Paulo J. Amorim Madeira, Paulo J. G. Mendes, Isabel Santos, M. Helena Garcia*, “Synthesis of organometallic ruthenium(II) complexes with strong activity against several human cancer cell lines”. Journal of Inorganic Biochemistry, 114, 2012, Pages 65-74
2011
[3] V. Moreno, M. Font-Bardia, T. Calvet, J. Lorenzo, F. X. Alvilés, M. H. Garcia, T. S. Morais, A. Valente, M. P. Robalo, “DNA interaction and cytotoxicity of new ruthenium (II) cyclopentadienyl derivative complexes containing heteroaromatic ligands”, J. Inorg. Biochem. 2011, 105, 241-249.
2010
[2] M. H. Garcia, A. Valente, P. Florindo, T. S. Morais, M. F. M. Piedade, M. T. Duarte, V. Moreno, F. X. Avilés, J. Loreno, “New ruthenium(II) mixed metallocene derived complexes: Synthesis, characterization by X-ray diffraction and evaluation on DNA interaction by atomic force microscopy”, Inorganica Chimica Acta 2010, 363, 3765-3775.
2009
[1] M. Helena Garcia,* Tânia S. Morais, Pedro Florindo, M. Fátima M. Piedade, Virtudes Moreno, Carlos Ciudad, Veronica Noe, “Inhibition of cancer cell growth by ruthenium(II) cyclopentadienyl derivative complexes with heteroaromatic ligands”, Journal of Inorganic Biochemistry, 103, 2009, Pages 354-361
[38] Ricardo G. Teixeira, Dimas C. Belisario, Xavier Fontrodona, Isabel Romero, Ana Isabel Tomaz, M. Helena Garcia, Chiara Riganti, Andreia Valente*, “Unprecedented collateral sensitivity for cisplatin-resistant lung cancer cells presented by new ruthenium organometallic compounds”, Inorganic Chemistry Frontiers, 2021. DOI: 10.1039/d0qi01344g
[37] Diogo Sequeira, Pedro V. Baptista, Ruben Valente, M. Fátima M. Piedade, M. Helena Garcia, Tânia S. Morais* and Alexandra R. Fernandes*, "Cu(i) complexes as new antiproliferative agents against sensitive and doxorubicin resistant colorectal cancer cells: synthesis, characterization, and mechanisms of action", Dalton Trans., 2021, 50, 1845-1865
2020
[36] Ricardo G. Teixeira, Fernanda Marques, M. Paula Robalo, Xavier Fontrodona, M. Helena Garcia, Simonetta Geninatti Crich, Clara Viñas*, Andreia Valente*, “Ruthenium carboranyl complexes with 2,2’-bipyridine derivatives for potential bimodal therapy application”, Accepted at RSC Advances, 2020.
[35] João Franco Machado, Diogo Sequeira, Fernanda Marques, M. Fátima M. Piedade, Maria J. Villa de Brito, M. Helena Garcia, Alexandra R. Fernandes* and Tânia S. Morais*, “New copper(i) complexes selective for prostate cancer cells”, Dalton Trans., 2020, 49, 12273-12286
[34] Pilon A, Brás AR, Côrte-Real L, Avecilla F, Costa PJ, Preto A, Garcia MH, Valente A*, “A new family of iron(II)-cyclopentadienyl compounds shows strong activity against colorectal and triple negative breast cancer cells”. Molecules. 2020 Mar 30;25(7). pii: E1592.
[33] João Franco Machado, Miguel Machuqueiro, Fernanda Marques, M. Paula Robalo, M. Fátima M. Piedade, M. Helena Garcia, João D. G. Correia*, Tânia S. Morais*, “Novel “ruthenium cyclopentadienyl”–peptide conjugate complexes against human FGFR(+) breast cancer”. Dalton Trans., 2020, 49, 5974-5987
2019
[32] Catarina Bravo, M. Paula Robalo, Fernanda Marques, Alexandra R. Fernandes, Diogo A. Sequeira, M. Fátima M. Piedade, M. Helena Garcia, Maria J. Villa de Brito*, Tânia S. Morais*, "First heterobimetallic Cu(i)–dppf complexes designed for anticancer applications: synthesis, structural characterization and cytotoxicity". New J. Chem., 2019, 43, 12308-12317
[31] L. Côrte-Real, B. Karas, A. R. Brás, A. Pilon, F. Avecilla, F. Marques, A. Preto, B. T. Buckley, K. R. Cooper, C. Doherty, M. H. Garcia*, A. Valente*, “Ruthenium-Cyclopentadienyl Bipyridine-Biotin Based Compounds: Synthesis and Biological Effect”. Inorganic Chemistry 2019, 58, 9135−9149.
[30] Lurdes Gano, Teresa Pinheiro, António P. Matos, Francisco Tortosa, Tiago F. Jorge, M. S. Gonçalves, M. Martins, Tânia S. Morais, Ana Isabel Tomaz, Andreia Valente, M. Helena Garcia, Fernanda Marques, “Antitumour and Toxicity Evaluation of a Ru(II)-Cyclopentadienyl Complex in a Prostate Cancer Model by Imaging Tools”. Anticancer Agents Med Chem. 2019 Mar 18.
[29] Brittany Karas, Leonor Côrte-Real, Andreia Valente, Keith R. Cooper, Brian T. Buckley, “Novel screening of transition metal-based anticancer compounds using zebrafish embryo larval assay and ICPMS analysis”. J. Appl. Toxicology 2019, 1-8.
[28] T. Moreira, R. Francisco, E. Comsa, S. Duban-Deweer, V. Labas, A.-P. Teixeira-Gomes, L. Combes-Soia, F. Marques, A. Matos, A. Favrelle, C. Rousseau, P. Zinck, P. Falson, M. H. Garcia, A. Preto, A. Valente*, “Polymer “ruthenium-cyclopentadienyl” conjugates - new emerging anti-cancer drugs”. European Journal of Medicinal Chemistry 2019, 168, 373-384.
[27] L. Côrte-Real, B. Karas, P. Gírio, A. Moreno, F. Avecilla, F. Marques, B. T. Buckley, K. R. Cooper, C. Doherty, P. Falson, M. H. Garcia*, A. Valente*, “Unprecedented inhibition of P-gp activity by a novel ruthenium-cyclopentadienyl compound bearing a bipyridine-biotin ligand”, European Journal of Medicinal Chemistry, 2019, 163, 853-863.
2018
[26] L. Côrte-Real, R. G. Teixeira, P. Gírio, E. Comsa, A. Moreno, R. Nasr, H. Baubichon-Cortay, F. Avecilla, F. Marques, M. P. Robalo, P. Mendes, J. P. P. Ramalho, M. H. Garcia, P. Falson*, A. Valente*, “Methyl-cyclopentadienyl Ruthenium Compounds with 2,2′-Bipyridine Derivatives Display Strong Anticancer Activity and Multidrug Resistance Potential”. Inorganic Chemistry, 2018, 57, 4629−4639.
[25] R. G. Teixeira, A. Sanches, L. Côrte-Real, R. Tatikonda, A. R. Brás, M. P. Robalo, F. Avecilla, M. H. Garcia, A. Preto, M. Haukka, A. Valente*, “Novel ruthenium methylcyclopentadienyl complex bearing a bipyridine perfluorinated ligand shows strong activity towards colorectal cancer cells”. European Journal of Medicinal Chemistry, 143, 2018, 503-514.
[24] Tânia S. Morais,* Yann Jousseaume, M. Fátima M. Piedade, Catarina Roma-Rodrigues, Alexandra R. Fernandes, Fernanda Marques, Maria J. Villa de Brito*, M. Helena Garcia, “Important cytotoxic and cytostatic effects of new copper(i)–phosphane compounds with N,N, N,O and N,S bidentate ligands”. Dalton Trans., 2018, 47, 7819-7829
2017
[23] A. Pilon, P. Gírio, G. Nogueira, F. Avecilla, H. Adams, J. Lorenzo, M. H. Garcia*, A. Valente*, “New iron cyclopentadienyl complexes bearing different phosphane co-ligands: structural factors vs. cytotoxicity”, Journal of Organometallic Chemistry, 852, 2017, 34-42.
[22] N. Mendes, F. Tortosa, A. Valente, F. Marques, A. Matos, T. S. Morais, A. I. Tomaz, F. Gärtner, M. H. Garcia, “In vivo Performance of a Ruthenium-cyclopentadienyl Compound in an Orthotopic Triple Negative Breast Cancer Model”, Anti-cancer Agents in Medicinal Chemistry Vol. 17, No. 1, 126-136, 2017.
[21] João Lopes, David Alves, Tânia S.Morais, Paulo J. Costa, M. Fátima M. Piedade, Fernanda Marques, Maria J. Villa de Brito, M. Helena Garcia, “New copper(I) and heteronuclear copper(I)–ruthenium(II) complexes: Synthesis, structural characterization and cytotoxicity”. Journal of Inorganic Biochemistry, 169, 2017, Pages 68-78.
2016
[20] G. Nogueira, O. Dömötör, A. Pilon, M. P. Robalo, F. Avecilla, M. H. Garcia, É. A. Enyedy*, A. Valente*, “η6-(2-Phenoxyethanol) ruthenium(II)-complexes of 2,2’-bipyridine and its derivatives: solution speciation and kinetic behaviour”, J. Organomet. Chem. 2016, 820, 20-29.
[19] T. S. Morais, A. Valente, A. Is. Tomaz, F. Marques, M. H. Garcia, “Tracking anti-tumor metallodrugs: promising agents with the Ru(II)- and Fe(II)-cyclopentadienyl scaffolds”, Future Medicinal Chemistry 2016, 8, 527-544. – selected as special report for the April issue
2015
[18] L. Côrte-Real, F. Marques, M. P. Robalo, G. Nogueira, F. Avecilla, F. C. Santos, A. I. Tomaz, M. H. Garcia*, A. Valente*, “The significant role of coligands in novel ruthenium(II)-cyclopentadienyl bipyridine derivatives: ranging from non-cytotoxic to highly cytotoxic compounds”, Journal of Inorganic Biochemistry 2015, 150, 148–159.
2014
[17] F. Marques, L. Côrte-Real, F. Mendes, J. Coimbra, T. Morais, A. I. Tomaz, A. Valente, M. H. Garcia, I. Santos, M. Bicho, “Anticancer Activity of Structural Related Ruthenium(II) Cyclopentadienyl complexes”, Journal of Biological Inorganic Chemistry 2014, 19(6):853-67.
[16] A. Valente,* M. H. Garcia, “Syntheses of macromolecular ruthenium compounds: a new approach to the search of anticancer drugs”, Inorganics 2014, 2, 96-114.
[15] A. Valente, A. M. Santos, L. Côrte-Real, M. P. Robalo, V. Moreno, M. Font-Bardia, T. Calvet, J. Lorenzo, M. H. Garcia, “New iron(II) cyclopentadienyl derivative complexes: synthesis and antitumor activity against human leukemia cancer cells”, Journal of Organometallic Chemistry 2014, 756, 52-60.
[14] Tânia S. Morais, Filipa C. Santos, Tiago F. Jorge, Leonor Côrte-Real, Paulo J. Amorim Madeira, Fernanda Marques, M. Paula Robalo, António Matos, Isabel Santos, M. Helena Garcia*, “New water-soluble ruthenium(II) cytotoxic complex: Biological activity and cellular distribution”. Journal of Inorganic Biochemistry, 130, 2014, Pages 1-14
2013
[13] A. Valente,* M. H. Garcia, F. Marques, Y. Miao, C. Rousseau, P. Zinck, “First polymer “ruthenium-cyclopentadienyl” complex as potential anticancer agent”, Journal of Inorganic Biochemistry 2013, 127, 79-81.
[12] C.P. Matos, A. Valente, F. Marques, M.P. Robalo, P. Adão, J.C. Pessoa, I. Santos, M.H. Garcia, A. I. Tomaz, “New polydentate Ru(III)-Salan complexes: Synthesis, characterization, anti-tumour activity and interaction with human serum proteins”, Inorganica Chimica Acta 2013, 394, 616-626.
[11] Tânia S.Morais, Filipa Santos, Leonor Côrte-Real, Fernanda Marques, M. Paula Robalo, Paulo J. Amorim Madeira, M. Helena Garcia, “Biological activity and cellular uptake of [Ru(η5-C5H5)(PPh3)(Me2bpy)][CF3SO3] complex”. Journal of Inorganic Biochemistry, 122, 2013, Pages 8-17
[10] Leonor Côrte-Real, António P. Matos, Irina Alho, Tânia S. Morais, Ana Isabel Tomaz, Maria Helena Garcia, Isabel Santos, Manuel P. Bicho, Fernanda Marques, “Cellular Uptake Mechanisms of an Antitumor Ruthenium Compound: The Endosomal/Lysosomal System as a Target for Anticancer Metal-Based Drugs”. Microscopy and Microanalysis, 19, 2013, pp. 1122-1130
[9] Tânia S. Morais, Filipa C. Santos, Leonor Corte-Real, M. Helena Garcia*, “Exploring the effect of the ligand design on the interactions between [Ru(η5-C5H5)(PPh3)(N,O)][CF3SO3] complexes and human serum albumin”. Journal of Inorganic Biochemistry, 129, 2013, Pages 94-101
[8] Ana Cristina Gonçalves, Tânia S. Morais, M. Paula Robalo, Fernanda Marques, Fernando Avecilla, Cristina P. Matos, Isabel Santos, Ana Isabel Tomaz, M. Helena Garcia*, “Important cytotoxicity of novel iron(II) cyclopentadienyl complexes with imidazole based ligands”. Journal of Inorganic Biochemistry, 129, 2013, Pages 1-8
2012
[7] Ana Isabel Tomaz,* Tamás Jakusch, Tânia S. Morais, Fernanda Marques, Rodrigo F. M. de Almeida, Filipa Mendes, Éva A. Enyedy, Isabel Santos, João Costa Pessoa, Tamás Kiss, M. Helena Garcia, “[RuII(η5-C5H5)(bipy)(PPh3)]+, a promising large spectrum antitumor agent: Cytotoxic activity and interaction with human serum albumin”. Journal of Inorganic Biochemistry, 117, 2012, Pages 261-269
[6] Paulo J. Amorim Madeira*, Tânia S. Morais, Tiago J. L. Silva, Pedro Florindo, M. Helena Garcia, “Gas‐phase behaviour of Ru(II) cyclopentadienyl‐derived complexes with N‐coordinated ligands by electrospray ionization mass spectrometry: fragmentation pathways and energetics”. Rapid Communications in Mass Spectrometry, 26, 2012, 1675-1686.
[5] Tânia S. Morais, M. Helena Garcia*, M. Paula Robalo, M. F. M. Piedade, M. Teresa Duarte, M. José Villa de Brito, Paulo J. Amorim Madeira, “Synthesis and structural characterization of new piano-stool ruthenium(II) complexes bearing 1-butylimidazole heteroaromatic ligand”. Journal of Organometallic Chemistry, 713, 2012, Pages 112-122
[4] Tânia S. Morais, Tiago J. L. Silva, Fernanda Marques, M. Paula Robalo, Fernando Avecilla, Paulo J. Amorim Madeira, Paulo J. G. Mendes, Isabel Santos, M. Helena Garcia*, “Synthesis of organometallic ruthenium(II) complexes with strong activity against several human cancer cell lines”. Journal of Inorganic Biochemistry, 114, 2012, Pages 65-74
2011
[3] V. Moreno, M. Font-Bardia, T. Calvet, J. Lorenzo, F. X. Alvilés, M. H. Garcia, T. S. Morais, A. Valente, M. P. Robalo, “DNA interaction and cytotoxicity of new ruthenium (II) cyclopentadienyl derivative complexes containing heteroaromatic ligands”, J. Inorg. Biochem. 2011, 105, 241-249.
2010
[2] M. H. Garcia, A. Valente, P. Florindo, T. S. Morais, M. F. M. Piedade, M. T. Duarte, V. Moreno, F. X. Avilés, J. Loreno, “New ruthenium(II) mixed metallocene derived complexes: Synthesis, characterization by X-ray diffraction and evaluation on DNA interaction by atomic force microscopy”, Inorganica Chimica Acta 2010, 363, 3765-3775.
2009
[1] M. Helena Garcia,* Tânia S. Morais, Pedro Florindo, M. Fátima M. Piedade, Virtudes Moreno, Carlos Ciudad, Veronica Noe, “Inhibition of cancer cell growth by ruthenium(II) cyclopentadienyl derivative complexes with heteroaromatic ligands”, Journal of Inorganic Biochemistry, 103, 2009, Pages 354-361
